The New England Journal of Medi­cine marks its 200th anniver­sary this year with a time­line cele­brating the scien­tific advances first described in its pages: the stetho­scope (1816), the use of ether for anes­thesia (1846), and disin­fecting hands and instru­ments before surgery (1867), among others. · Go to History of medical discov­eries →